Effect of omega-3 supplementation versus placebo on acylation stimulating protein receptor gene expression in type 2 diabetics

نویسندگان

  • Payam Farahbakhsh-Farsi
  • Mahmoud Djalali
  • Fariba Koohdani
  • Ali Akbar Saboor-Yaraghi
  • Mohammad Reza Eshraghian
  • Mohammad Hassan Javanbakht
  • Maryam Chamari
  • Abolghassem Djazayery
چکیده

BACKGROUND This randomized controlled trial investigated the role of omega-3 supplementation on C5L2 gene expression in type 2 diabetics. METHODS Subjects in the omega-3 group received 4 g omega-3 per day and subjects in the placebo group took four capsules of placebo per day for 10 weeks. Gene expression was measured by RT- PCR at the beginning and end of the study. RESULTS The results of this study show depletion in the omega-3 group, but the mean difference between two groups was not significant. CONCLUSIONS Understanding the effect of the omega-3 pathway could contribute to targeting treatment of diabetes and its comorbidities.

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عنوان ژورنال:

دوره 13  شماره 

صفحات  -

تاریخ انتشار 2014